Daryl Hannah was born and raised in Chicago, Illinois. She attend the University of Southern California (USC) and made her film debut in the Brian De Palma film The Fury (1978). She starred in such films as Ron Howard's Splash (1984) and 'Herbert Ross' Steel Magnolias (1989). She won the Jury Award from the Berlin International Film Festival for Best Short in 1994 for a film titled The Last Supper (1993), which she directed, wrote, and produced.
| Movie | Naya: Legend of the Golden Dolphin | 2026 | |
| Movie | Buckle Up | Angel | 2023-07-06 |
| Movie | American Badass: A Michael Madsen Retrospective | Self | 2022-08-15 |
| Movie | QT8: The First Eight | Self (archive footage) | 2019-10-21 |
| Movie | Paradox | Angel | 2018-03-15 |
| Movie | Papa | Sarah Freidman | 2018-06-14 |
| Movie | The Slider | Carol | 2017-12-31 |
| Movie | A Hitman in London | Zhanna | 2015-03-12 |
| Movie | I Am Michael | Deborah | 2015-01-29 |
| Movie | Father Rupert Mayer | Joanna Sebastian | 2015-05-01 |
| Series | Sense8 | Angelica Turing | 2015-06-05 |
| Movie | Awaken | Mao | 2015-07-07 |
| Movie | Sicilian Vampire | Carmelina Trafficante | 2015-11-03 |
| Movie | 2047: Sights of Death | Major Anderson | 2014-06-13 |
| Movie | Pussy Riot: The Movement | Narrator | 2013-05-10 |
| Movie | American Mustang | The Advocate | 2013-11-07 |
| Movie | The Hot Flashes | Ginger Peabody | 2013-07-12 |
| Movie | Garbage | Daryl | 2013-01-01 |
| Movie | Zombie Night | Birdie | 2013-10-08 |
| Movie | Arise | Narrator | 2013-09-20 |
| Movie | Social Nightmare | Susan Hardy | 2013-08-31 |
| Movie | Eldorado | The Stranger | 2012-01-30 |
| Movie | A Closed Book | Jane Ryder | 2012-07-13 |
| Movie | The Carbon Rush | Narrator | 2012-11-07 |
| Movie | Pipe Dreams | Narrator | 2011-01-01 |
| Movie | Kill Bill: The Whole Bloody Affair | Elle Driver (California Mountain Snake) | 2011-03-27 |
| Movie | Celebrity Nude Revue: Easy 80's Volume 1 | Self (archive footage) | 2011-10-26 |
| Movie | Lovemakers | Mimi | 2011-12-15 |
| Movie | Furry Vengeance | Felder | 2010-04-30 |
| Movie | Storm Seekers | Leah Kaplan | 2009-04-05 |
| Series | Live from Studio Five | Unknown | 2009-09-14 |
| Series | Alan Carr: Chatty Man | Unknown | 2009-06-14 |
| Movie | Amazing Racer | Rita Baker | 2009-04-23 |
| Movie | Starz Inside - Unforgettably Evil | Self | 2009-07-26 |
| Movie | Waking Sleeping Beauty | Madison (archive footage) | 2009-09-05 |
| Movie | Vice | Salt | 2008-05-09 |
| Movie | Shark Swarm | Brook Wilder | 2008-03-09 |
| Movie | IMAX Dolphins and Whales: Tribes of the Ocean | Narrator (voice) | 2008-02-15 |
| Movie | The Devil's Ground | Carrie Mitchel | 2008-05-19 |
| Movie | Kung Fu Killer | Jane | 2008-08-17 |
| Movie | The Garden | Self | 2008-08-17 |
| Movie | Dark Honeymoon | Jan | 2008-07-22 |
| Series | Kung Fu Killer | Jane | 2008-08-17 |
| Movie | The Poet | Marlene Konig | 2007-08-07 |
| Movie | Being Michael Madsen | Self | 2007-09-28 |
| Movie | Dangerous Days: Making Blade Runner | Self | 2007-12-18 |
| Movie | All the Good Ones Are Married | Alex | 2007-09-29 |
| Movie | Final Days of Planet Earth | Liz Quinlan | 2006-03-15 |
| Movie | Keeping Up with the Steins | Sandy / Sacred | 2006-05-12 |
| Movie | Olé | Maggie Granger | 2006-12-15 |
| Movie | Making a 'Splash' | Self - 'Madison' | 2004-03-30 |
| Movie | The Life | Adriana | 2004-04-16 |
| Movie | Silver City | Maddy Pilager | 2004-09-17 |
| Movie | Kill Bill: Vol. 2 | Elle Driver 'California Mountain Snake' | 2004-04-16 |
| Movie | Stories of Lost Souls | Herself | 2004-11-12 |
| Movie | The Big Empty | Stella | 2003-05-16 |
| Series | Jimmy Kimmel Live! | Unknown | 2003-01-26 |
| Movie | Northfork | Flower Hercules | 2003-07-11 |
| Movie | The Job | CJ March | 2003-05-16 |
| Series | The Ellen DeGeneres Show | Unknown | 2003-09-08 |
| Movie | Bare Knuckle Filming: The Construction of Northfork | 2003-12-30 | |
| Movie | Kill Bill: Vol. 1 | Elle Driver | 2003-10-10 |
| Movie | Casa de los Babys | Skipper | 2003-09-19 |
| Movie | A Walk to Remember | Cynthia Carter | 2002-01-25 |
| Movie | Hard Cash | Virginia | 2002-02-15 |
| Series | V Graham Norton | Unknown | 2002-05-06 |
| Movie | Cowboy Up | Celia Jones | 2002-09-03 |
| Movie | Searching for Debra Winger | Self | 2002-07-13 |
| Movie | Jackpot | Bobbi | 2001-07-27 |
| Series | Good Day Live | Unknown | 2001-09-17 |
| Movie | Dancing at the Blue Iguana | Angel | 2001-10-10 |
| Series | Jack and the Beanstalk: The Real Story | Thespee | 2001-12-02 |
| Movie | Hide and Seek | Anne White | 2000-05-23 |
| Movie | On the Edge of 'Blade Runner' | Self | 2000-07-15 |
| Movie | First Target | Alex McGregor | 2000-10-15 |
| Movie | Wildflowers | Sabine | 2000-09-01 |
| Movie | Zapatista | Narrator (voice) | 1999-01-01 |
| Movie | Speedway Junky | Veronica | 1999-02-11 |
| Movie | My Favorite Martian | Lizzie | 1999-02-11 |
| Movie | Diplomatic Siege | Erica Long | 1999-12-17 |
| Movie | The Gingerbread Man | Lois Harlan | 1998-01-23 |
| Movie | Rescuers: Stories of Courage - Two Families | Maria Althoff | 1998-01-01 |
| Movie | The Real Blonde | Kelly | 1998-02-27 |
| Movie | Rear Window | Claudia Henderson | 1998-11-22 |
| Movie | Addams Family Reunion | Morticia Addams | 1998-12-23 |
| Movie | Hi-Life | Maggie | 1998-11-27 |
| Series | Gun | 1997-04-12 | |
| Series | The Last Don | Athena Aquitane | 1997-05-11 |
| Series | The View | Unknown | 1997-08-11 |
| Series | Muppets Tonight | Unknown | 1996-03-08 |
| Movie | The Good, The Bad, and the Beautiful | Self | 1996-03-17 |
| Series | E! True Hollywood Story | Unknown | 1996-08-21 |
| Movie | The Last Days of Frankie the Fly | Margaret | 1996-10-24 |
| Movie | One Hundred and One Nights | Mute Actress in Hollywood (uncredited) | 1995-01-25 |
| Movie | The Tie That Binds | Leann Netherwood | 1995-09-08 |
| Movie | Grumpier Old Men | Melanie Gustafson | 1995-12-22 |
| Movie | Two Much | Liz | 1995-12-01 |
| Movie | The Little Rascals | Miss Crabtree | 1994-08-05 |
| Movie | Attack of the 50 Ft. Woman | Nancy Archer | 1994-09-28 |
| Series | Frasier | Caller #2 | 1993-09-16 |
| Movie | Grumpy Old Men | Melanie | 1993-12-25 |
| Movie | Memoirs of an Invisible Man | Alice Monroe | 1992-02-28 |
| Movie | The Best of Disney: 50 Years of Magic | Self | 1991-05-20 |
| Movie | At Play in the Fields of the Lord | Andy Huben | 1991-12-06 |
| Movie | Crazy People | Kathy Burgess | 1990-04-13 |
| Movie | Steel Magnolias | Annelle Dupuy | 1989-11-15 |
| Movie | Crimes and Misdemeanors | Lisa Crosley | 1989-10-13 |
| Series | America's Most Wanted | Unknown | 1988-02-07 |
| Movie | High Spirits | Mary Plunkett | 1988-11-18 |
| Movie | Wall Street | Darien Taylor | 1987-12-10 |
| Movie | Roxanne | Roxanne Kowalski | 1987-06-19 |
| Movie | The Clan of the Cave Bear | Ayla | 1986-01-17 |
| Movie | Legal Eagles | Chelsea Deardon | 1986-06-18 |
| Movie | Splash | Madison | 1984-03-09 |
| Movie | Reckless | Tracey Prescott | 1984-02-03 |
| Movie | The Pope of Greenwich Village | Diane | 1984-06-22 |
| Movie | The Final Terror | Windy | 1983-05-01 |
| Movie | Paper Dolls | Taryn Blake | 1982-05-24 |
| Movie | Blade Runner | Pris | 1982-06-25 |
| Movie | Summer Lovers | Cathy Featherstone | 1982-07-16 |
| Movie | Hard Country | Loretta | 1981-04-01 |
| Movie | The Fury | Pam | 1978-03-10 |
| Series | The Hollywood Greats | Unknown | 1977-08-04 |