James Gleason was born in New York City to William Gleason and Mina Crolius, who were both in the theatre. He was married to Lucile Gleason (born Lucile Webster), and had a son, Russell Gleason. As a young man James fought in the Spanish-American War. After the war he joined the stock company at the Liberty Theater in Oakland, California, which his parents were running. James and his wife then moved to Portland, Oregon, where they played in stock at the Baker Theater. For several years afterward they toured in road shows until James enlisted in the army during World War I. When he returned he appeared on the stage in "The Five Million." He then turned to writing, including "Is Zat So", which he produced for the NY stage. He also wrote and acted in "The Fall Guy" and "The Shannons on Broadway." Next he wrote The Broadway Melody (1929) for MGM. He collaborated, in 1930, on The Swellhead (1930), Dumbbells in Ermine (1930), What a Widow! (1930), Rain or Shine (1930) and His First Command (1929). He and his wife were then contracted to Pathe, Lucille to act, and James (or Jimmie as he was known) as a writer. Probably his most famous acting role was as Max Corkle, the manager of Joe Pendleton who was wrongly plucked from this life into the next, in the hit fantasy Here Comes Mr. Jordan (1941).
| Movie | Rules Don't Apply | Doctor Crone | 2016-11-23 |
| Movie | Awaken | Willy | 2013-04-09 |
| Movie | Stealing Roses | Marco | 2012-06-01 |
| Series | FlashForward | Rev. David Mullen | 2009-09-24 |
| Movie | American Dreamz | Journalist | 2006-03-04 |
| Movie | S1m0ne | Reporter | 2002-08-23 |
| Movie | Shadow of the Blair Witch | Jeff Schoene | 2000-10-22 |
| Movie | Why Do Fools Fall In Love | Stage Manager | 1998-08-28 |
| Movie | Mother | Waiter | 1996-12-25 |
| Movie | Sawbones | Coroner | 1995-07-25 |
| Movie | Revenge of the Nerds IV: Nerds In Love | 1994-05-09 | |
| Movie | Bloodlines: Murder in the Family | Controller | 1993-03-01 |
| Movie | Jason Goes to Hell: The Final Friday | Agent Abernathy | 1993-08-13 |
| Movie | Star | The Director | 1993-09-20 |
| Movie | For Richer, for Poorer | Salesman | 1992-01-01 |
| Movie | Boris and Natasha | Taxi Driver | 1992-04-17 |
| Movie | My Demon Lover | Alert Cop | 1987-04-24 |
| Movie | The World's Greatest Lover | Room Clerk | 1977-12-18 |
| Movie | Hollywood My Home Town | Self (archive footage) | 1965-12-31 |
| Movie | The Female Animal | Tom Maloney | 1958-01-22 |
| Movie | Man or Gun | Sheriff Jim Jackson | 1958-05-30 |
| Movie | Rock-a-Bye Baby | Doc Simpkins | 1958-07-23 |
| Movie | The Last Hurrah | Cuke Gillen | 1958-12-31 |
| Movie | Money, Women and Guns | Henry Devers | 1958-10-01 |
| Movie | Once Upon a Horse... | Postmaster | 1958-09-01 |
| Movie | Spring Reunion | Collie | 1957-03-01 |
| Movie | Loving You | Carl Meade | 1957-07-09 |
| Series | Leave It to Beaver | Unknown | 1957-10-04 |
| Movie | Man in the Shadow | Hank James | 1957-12-12 |
| Movie | Star in the Dust | Orval Jones | 1956-06-13 |
| Movie | The Night of the Hunter | Uncle Birdie Steptoe | 1955-07-27 |
| Series | The Millionaire | Unknown | 1955-01-19 |
| Series | Cheyenne | Unknown | 1955-09-20 |
| Movie | The Girl Rush | Ether Ferguson | 1955-09-16 |
| Series | Alfred Hitchcock Presents | Unknown | 1955-10-02 |
| Movie | Hollywood Thrill-Makers | Risky Russell | 1954-01-15 |
| Movie | Suddenly | Peter 'Pop' Benson | 1954-09-17 |
| Series | Climax! | Unknown | 1954-10-07 |
| Movie | Forever Female | Eddie Woods | 1953-11-28 |
| Movie | We're Not Married! | Duffy | 1952-07-11 |
| Movie | The Story of Will Rogers | Bert Lynn | 1952-07-17 |
| Series | Cavalcade of America | Unknown | 1952-10-01 |
| Movie | What Price Glory | General Cokely | 1952-08-22 |
| Series | This Is Your Life | Unknown | 1952-10-01 |
| Series | Racket Squad | Unknown | 1951-06-07 |
| Movie | Joe Palooka in Triple Cross | Knobby Walsh | 1951-09-16 |
| Movie | Come Fill the Cup | Charley Dolan | 1951-10-24 |
| Movie | I'll See You in My Dreams | Fred Townsend | 1951-12-06 |
| Movie | The Yellow Cab Man | Mickey Corkins | 1950-03-25 |
| Movie | Key to the City | Sergeant Hogan | 1950-02-02 |
| Movie | Riding High | Racing Secretary | 1950-04-12 |
| Series | The Colgate Comedy Hour | Unknown | 1950-09-10 |
| Movie | Joe Palooka in the Squared Circle | Knobby Walsh | 1950-11-04 |
| Movie | The Jackpot | Harry Summers | 1950-11-01 |
| Movie | A Guy Named Joe | “Nails” Kilpatrick | 1949-01-08 |
| Movie | Bad Boy | Chief | 1949-02-22 |
| Movie | Miss Grant Takes Richmond | Timothy Gleason | 1949-10-20 |
| Movie | The Life of Riley | Gillis | 1949-04-16 |
| Movie | Take One False Step | Captain Gledhill | 1949-08-14 |
| Movie | Smart Woman | Sam Corkle | 1948-04-30 |
| Movie | The Dude Goes West | Sam Briggs | 1948-05-30 |
| Movie | The Return of October | Uncle Willie Ramsey | 1948-10-26 |
| Movie | When My Baby Smiles at Me | Lefty Moore | 1948-11-10 |
| Movie | The Homestretch | Doc Kilborne | 1947-05-04 |
| Movie | Down to Earth | Max Corkle | 1947-08-21 |
| Movie | The Bishop's Wife | Sylvester | 1947-12-25 |
| Movie | Tycoon | Pop Mathews | 1947-12-27 |
| Movie | The Hoodlum Saint | Snarp | 1946-04-04 |
| Movie | The Well Groomed Bride | Captain Hornby | 1946-05-17 |
| Movie | Home Sweet Homicide | Sgt. O'Hare | 1946-10-02 |
| Movie | Lady Luck | Sacramento Sam | 1946-10-30 |
| Movie | A Tree Grows in Brooklyn | McGarrity | 1945-02-28 |
| Movie | This Man's Navy | Jimmy Shannon | 1945-01-04 |
| Movie | The Clock | Al Henry | 1945-05-25 |
| Movie | Captain Eddie | Tom Clark | 1945-06-18 |
| Movie | Arsenic and Old Lace | Lt. Rooney | 1944-09-01 |
| Movie | Once Upon a Time | Moke McGillicuddy | 1944-06-29 |
| Movie | The Keys of the Kingdom | Rev. Dr. Wilbur Fiske | 1944-12-15 |
| Movie | Crash Dive | Chief Mike 'Mac' McDonnell | 1943-04-22 |
| Movie | A Date with the Falcon | Inspector Michael 'Mike' O'Hara | 1942-01-16 |
| Movie | My Gal Sal | Pat Hawley | 1942-04-30 |
| Movie | Hay Foot | Colonel J. A. Barkley | 1942-01-02 |
| Movie | Footlight Serenade | Bruce McKay | 1942-08-01 |
| Movie | Manila Calling | Tim O'Rourke | 1942-10-16 |
| Movie | The Falcon Takes Over | Inspector Mike O'Hara | 1942-05-29 |
| Movie | Tales of Manhattan | Joe - Mission Aid Society | 1942-08-05 |
| Movie | Affectionately Yours | 'Chet' Phillips | 1941-05-10 |
| Movie | Meet John Doe | Henry Connell | 1941-03-14 |
| Movie | Tanks a Million | Col. 'Spitfire' Barkley | 1941-09-12 |
| Movie | Here Comes Mr. Jordan | Max Corkle | 1941-08-07 |
| Movie | Babes on Broadway | Thornton Reed | 1941-12-31 |
| Movie | Breakdowns of 1941 | Self (archive footage) (uncredited) | 1941-11-14 |
| Movie | Nine Lives Are Not Enough | Sergeant Daniels | 1941-09-20 |
| Movie | Grandpa Goes To Town | Joe Higgins | 1940-04-13 |
| Movie | Should Husbands Work? | Joe Higgins | 1939-07-26 |
| Movie | On Your Toes | Phil Dolan Sr. | 1939-10-14 |
| Movie | My Wife's Relatives | Joe Higgins | 1939-05-20 |
| Movie | The Covered Trailer | Joe Higgins | 1939-11-10 |
| Movie | Money To Burn | Joe Higgins | 1939-12-31 |
| Movie | The Higgins Family | Joe Higgins | 1938-03-28 |
| Movie | Screen Snapshots Series 17, No. 6 | Self | 1938-02-04 |
| Movie | Army Girl | Hennessy | 1938-08-11 |
| Movie | Cinema Circus | Himself | 1937-01-27 |
| Movie | Forty Naughty Girls | Police Insp. Oscar Piper | 1937-09-24 |
| Movie | Manhattan Merry-Go-Round | Danny The Duck | 1937-11-26 |
| Movie | Yours for the Asking | Saratoga | 1936-07-23 |
| Movie | Murder on a Bridle Path | Police Insp. Oscar Piper | 1936-04-17 |
| Movie | The Ex-Mrs. Bradford | Inspector Corrigan | 1936-04-24 |
| Movie | Don't Turn 'em Loose | Detective Daniels | 1936-09-18 |
| Movie | The Plot Thickens | Police Insp. Oscar Piper | 1936-12-11 |
| Movie | The Big Game | George Scott | 1936-10-09 |
| Movie | Murder on a Honeymoon | Police Insp. Oscar Piper | 1935-02-22 |
| Movie | West Point of the Air | Joe 'Bags' | 1935-03-23 |
| Movie | Hot Tip | Jimmy McGill | 1935-08-20 |
| Movie | We're Only Human | Detective Danny Walsh | 1935-12-27 |
| Movie | Hollywood Hobbies | Himself | 1935-07-05 |
| Movie | The Meanest Gal in Town | Duke Slater | 1934-01-12 |
| Movie | Search for Beauty | Dan Healy | 1934-02-02 |
| Movie | Change of Heart | Hot Dog Vendor (uncredited) | 1934-05-18 |
| Movie | Murder on the Blackboard | Police Insp. Oscar Piper | 1934-06-15 |
| Movie | Orders Is Orders | Ed Waggermeyer | 1933-07-18 |
| Movie | Clear All Wires! | Lefty Williams | 1933-02-24 |
| Movie | Hoopla | Jerry | 1933-11-30 |
| Movie | High Hats and Low Brows | Danny Ruff | 1932-07-10 |
| Movie | Lady and Gent | Pin Streaver | 1932-07-10 |
| Movie | Fast Companions | Silk Henley | 1932-06-22 |
| Movie | Blondie of the Follies | Pa McClune | 1932-09-01 |
| Movie | The All-American | Chick Knipe | 1932-10-01 |
| Movie | The Crooked Circle | Arthur Crimmer | 1932-09-25 |
| Movie | The Penguin Pool Murder | Police Insp. Oscar Piper | 1932-12-09 |
| Movie | The Devil Is Driving | 'Beef' Evans | 1932-12-09 |
| Movie | Yoo-Hoo | Jimmy Gleason | 1932-10-04 |
| Movie | Beyond Victory | Jim Mobley | 1931-04-03 |
| Movie | A Free Soul | Eddie | 1931-06-02 |
| Movie | It's a Wise Child | Cool Kelly | 1931-04-10 |
| Movie | Sweepstakes | Sleepy Jones | 1931-07-10 |
| Movie | Suicide Fleet | Skeets | 1931-11-20 |
| Movie | The Big Gamble | Fred 'Squint' Dugan | 1931-09-04 |
| Movie | Puttin' on the Ritz | James 'Jimmy' Tierney | 1930-02-19 |
| Movie | Dumb-bells in Ermine | Mike | 1930-05-10 |
| Movie | The Matrimonial Bed | Gustave Corton | 1930-08-01 |
| Movie | Her Man | Steve | 1930-09-21 |
| Movie | The Broadway Melody | Music Publisher (uncredited) | 1929-02-08 |
| Movie | Oh, Yeah! | Dusty | 1929-10-19 |
| Movie | Polly of the Follies | Paul Gordon | 1922-01-30 |