During the Japanese occupation, she attended Andjar Asmara's theater school. In 1948, she made her film debut in Air Mata Mengalir di Tjitaroem, using the name Sofia Waldy. After a divorce from first husband S. Waldy, she married actor W.D. Mochtar and began professionally using the name Sofia W.D., starting in 1964. Not just an award-winning actress of both stage and screen who appeared in well over 100 films, Sofia also became one of Indonesia's first female directors with 1962's Badai-Selatan ("Southern Storm"), a horror tale that was nominated for the Golden Berlin Bear Award at the Berlin International Film Festival. She produced, wrote and even operated the camera on a number of films, and was the director of the production companies Film Capital, Libra Film and Dirgahayu Jaya Film over the course of her busy and prolific career.
| Movie | For You, I'll Give Everything | 1984-12-27 | |
| Movie | Treachery of G30S/PKI | 1984-11-01 | |
| Movie | Lara jonggrang (Candi Prambanan) | 1983-01-01 | |
| Movie | The Five Faces of Kadarwati | Makiko | 1983-01-01 |
| Movie | Behind the Mosquito Net | Ibu Martini | 1983-01-01 |
| Movie | Fatima | 1983-01-01 | |
| Movie | The White Crocodile | 1982-02-01 | |
| Movie | Roro Mendut | (as Sofia) | 1982-01-02 |
| Movie | Wedding 83 | 1982-12-30 | |
| Movie | The Queen of Black Magic | 1981-01-01 | |
| Movie | Mystics in Bali | Old Leák Queen | 1981-01-01 |
| Movie | Amalia, Bachelor of Law | 1981-12-31 | |
| Movie | Queen of the South Coast | Maryam | 1980-01-01 |
| Movie | Lady in a Trap | Mrs. Prawiro | 1980-01-01 |
| Movie | Yeah, Right... | 1979-03-01 | |
| Movie | Antidote for Witchcraft | 1979-01-01 | |
| Movie | The Temptation of the Demon Woman | Siluman | 1978-03-31 |
| Movie | The Midwife: Praji Magic | 1977-01-01 | |
| Movie | Christina | 1977-01-01 | |
| Movie | Greedy Appetite | Nenek | 1977-01-01 |
| Movie | Badai Pasti Berlalu | 1977-11-28 | |
| Movie | Max Havelaar: or, The Coffee Auctions of the Dutch Trading Company | Inah | 1976-09-09 |
| Movie | Malam Pengantin | 1975-05-08 | |
| Movie | The Earth Gets Hotter | 1973-01-01 | |
| Movie | The Lady | 1973-01-01 | |
| Movie | Lagu Untukmu | 1973-03-22 | |
| Movie | Hatiku dalam Hatimu | 1973-08-30 | |
| Movie | Timang-timang Anakku Sayang | Sofia | 1973-05-23 |
| Movie | The Moon on the Graveyard | 1973-03-31 | |
| Movie | River of Love | 1971-01-01 | |
| Movie | Romansa | 1970-08-04 | |
| Movie | The Longest Dark | 1970-01-01 | |
| Movie | Samiun dan Dasima | Hayati | 1970-05-05 |
| Movie | Tjita-Tjita Ajah | Bu Slamet | 1960-03-08 |
| Movie | Gending Sriwidjaja | 1958-03-23 | |
| Movie | Biola | 1957-08-12 | |
| Movie | Golden Queen | (as Sofia) | 1955-01-01 |
| Movie | Djakarta di Waktu Malam | 1954-07-06 | |
| Movie | Kali Brantas (Melati Kali Brantas) | Sunarti | 1954-10-15 |
| Movie | Bulan Purnama | Putri Amidra | 1953-02-04 |
| Movie | Dendang Sajang | Halimah | 1953-10-14 |