Adrien Nicholas Brody was born in Woodhaven, Queens, New York, the only child of retired history professor Elliot Brody and Hungarian-born photographer Sylvia Plachy. He accompanied his mother on assignments for the Village Voice, and credits her with making him feel comfortable in front of the camera. Adrien attended the American Academy of Dramatic Arts and LaGuardia High School for the Performing Arts in New York.
| Movie | Evolution of the Species: Predators Reborn | Self | 2027 |
| Movie | Motor City | 2025-08-30 | |
| Movie | The Brutalist | László Tóth | 2024-12-20 |
| Movie | Ghosted | Leveque | 2023-04-18 |
| Movie | Fool's Paradise | Chad Luxt | 2023-05-12 |
| Movie | Manodrome | Dan | 2023-11-10 |
| Movie | Asteroid City | Schubert Green | 2023-06-08 |
| Series | Winning Time: The Rise of the Lakers Dynasty | Pat Riley | 2022-03-06 |
| Movie | Clean | Clean | 2022-01-28 |
| Movie | See How They Run | Leo Köpernick | 2022-09-09 |
| Movie | Blonde | The Playwright | 2022-09-16 |
| Series | Chapelwaite | Captain Charles Boone | 2021-08-22 |
| Movie | Trintignant by Trintignant | Self (archive footage) | 2021-10-11 |
| Movie | The French Dispatch of the Liberty, Kansas Evening Sun | Julian Cadazio | 2021-10-21 |
| Movie | Spider-Man: Far From Home | Norman Osborn | 2019-06-28 |
| Movie | Who Will Write Our History? | Emanuel Ringelblum (voice) | 2018-07-21 |
| Movie | Air Strike | Steve | 2018-10-26 |
| Movie | Bullet Head | Stacy | 2017-12-07 |
| Movie | Manhattan Night | Porter Wren | 2016-05-20 |
| Movie | The Mascot | Adam | 2015-06-27 |
| Movie | Boredom | Danny | 2015-06-27 |
| Movie | Dragon Blade | Tiberius | 2015-02-19 |
| Movie | Septembers of Shiraz | Isaac | 2015-09-15 |
| Movie | The Library Book | Desmond | 2015-06-27 |
| Movie | Backtrack | Peter Bower | 2015-07-25 |
| Movie | The Grand Budapest Hotel | Dmitri | 2014-02-26 |
| Movie | And the Oscar Goes To... | Self (archive footage) | 2014-02-01 |
| Series | Houdini | Harry Houdini | 2014-09-01 |
| Movie | Third Person | Sean | 2014-06-20 |
| Movie | American Heist | Frankie | 2014-09-11 |
| Movie | InAPPropriate Comedy | Flirty Harry | 2013-03-22 |
| Movie | Love, Marilyn | Self | 2013-05-30 |
| Series | Peaky Blinders | Luca Changretta | 2013-09-12 |
| Movie | Roman Polanski: A Film Memoir | Self (archive footage) | 2012-10-09 |
| Movie | Back to 1942 | Theodore Harold White | 2012-11-01 |
| Movie | Detachment | Henry Barthes | 2011-04-24 |
| Movie | Midnight in Paris | Salvador Dalí | 2011-05-11 |
| Movie | Splice | Clive | 2010-06-03 |
| Movie | Wrecked | Man | 2010-04-01 |
| Movie | High School | Psycho Ed | 2010-06-03 |
| Movie | Giallo | Inspector Enzo Avolfi | 2010-03-13 |
| Movie | Predators | Royce | 2010-07-07 |
| Movie | The Making of 'The Darjeeling Limited' | Self - Peter | 2010-10-12 |
| Movie | The Experiment | Travis | 2010-07-15 |
| Movie | Fantastic Mr. Fox | Field Mouse (voice) | 2009-10-14 |
| Movie | The Brothers Bloom | Bloom | 2008-09-09 |
| Movie | A Matador's Mistress | Manuel Rodríguez Sánchez "Manolete" | 2008-09-06 |
| Movie | Cadillac Records | Leonard Chess | 2008-12-05 |
| Movie | Gumball 3000: Drivin' Me Crazy | Self | 2007-05-27 |
| Movie | The Darjeeling Limited | Peter | 2007-09-07 |
| Movie | Hollywoodland | Louis Simo | 2006-08-31 |
| Movie | Recreating the Eighth Wonder: The Making of 'King Kong' | Self | 2006-11-14 |
| Movie | Deconstructing 'The Village' | Self | 2005-01-11 |
| Movie | The Jacket | Jack Starks | 2005-03-04 |
| Movie | King Kong: Peter Jackson's Production Diaries | Self | 2005-12-13 |
| Movie | Gumball 3000: 6 Days in May | Self | 2005-05-09 |
| Movie | King Kong | Jack Driscoll | 2005-12-12 |
| Movie | The Buried Secret of M. Night Shyamalan | Self | 2004-06-18 |
| Movie | The Village | Noah Percy | 2004-07-30 |
| Movie | Love the Hard Way | Jack Grace | 2003-03-27 |
| Movie | The Singing Detective | First Hood | 2003-10-24 |
| Movie | The Pianist | Władysław 'Władek' Szpilman | 2002-09-17 |
| Movie | Dummy | Steven Schoichet | 2002-09-12 |
| Movie | Ken and Rosa | Himself | 2001-10-25 |
| Movie | The Affair of the Necklace | Count Nicolas De La Motte | 2001-11-30 |
| Movie | Harrison's Flowers | Kyle Morris | 2000-09-23 |
| Movie | Restaurant | Chris Calloway | 2000-01-28 |
| Movie | Bread and Roses | Sam Shapiro | 2000-09-14 |
| Movie | Six Ways to Sunday | Arnie Finklestein | 1999-03-05 |
| Movie | Summer of Sam | Ritchie | 1999-06-28 |
| Movie | Oxygen | Harry | 1999-11-12 |
| Movie | Liberty Heights | Van Kurtzman | 1999-11-17 |
| Movie | Mythos Hollywood - Das Geheimnis des Erfolgs | Self | 1998-01-01 |
| Movie | The Thin Red Line | Cpl. Geoffrey Fife | 1998-12-23 |
| Movie | The Last Time I Committed Suicide | Ben | 1997-06-20 |
| Movie | The Undertaker's Wedding | Mario Bellini | 1997-08-01 |
| Movie | Bullet | Ruby Stein | 1996-03-01 |
| Movie | Solo | Dr. Bill Stewart, Solo's Designer | 1996-08-23 |
| Movie | Ten Benny | Ray Diglovanni | 1995-04-09 |
| Movie | Angels in the Outfield | Danny Hemmerling | 1994-07-15 |
| Series | Rebel Highway | Skinny | 1994-07-07 |
| Movie | Natural Born Killers | Wayne Gale's Cameraman | 1994-08-26 |
| Movie | Jailbreakers | Skinny | 1994-09-09 |
| Movie | King of the Hill | Lester | 1993-08-20 |
| Movie | The Boy Who Cried Bitch | Eddie | 1991-10-11 |
| Movie | New York Stories | Mel | 1989-03-10 |
| Movie | Home at Last | Billy | 1988-01-09 |